4-acylamino-6-arylfuro[2,3-d]pyrimidines: potent and selective glycogen synthase kinase-3 inhibitorsMAEDA, Yutaka; NAKANO, Masato; SATO, Hideyuki et al.Bioorganic & medicinal chemistry letters (Print). 2004, Vol 14, Num 15, pp 3907-3911, issn 0960-894X, 5 p.Article

Anti-varicella-zoster virus bicyclic nucleosides : replacement of furo by pyrro base reduces antiviral potencyMCGUIGAN, C; PATHIRANA, R. N; JONES, G et al.Antiviral chemistry & chemotherapy. 2000, Vol 11, Num 5, pp 343-348, issn 0956-3202Article

Synthesis and Antiviral Activity of the Carbocyclic Analogue of the Highly Potent and Selective Anti-VZV Bicyclo Furano PyrimidinesMIGLIORE, Marco D; ZONTA, Nicola; MCGUIGAN, Christopher et al.Journal of medicinal chemistry (Print). 2007, Vol 50, Num 26, pp 6485-6492, issn 0022-2623, 8 p.Article

HETEROCYCLEN AUS LACTONEN, LACTAMEN UND THIOLLACTONEN. XV. ZUR REAKTION VON ALPHA -ACYL- UND ALPHA -ALKOXYAETHYLIDEN-DELTA ^BETA,GAMMA )-BUTENOLIDEN MIT AMIDINEN, GUANIDINEN UND HYDRAZINEN = HETEROCYCLES A PARTIR DE LACTONES, LACTAMES ET THIOLACTONES. XV. REACTION DES ALPHA -ACYL ET ALPHA -ALCOXYETHYLIDENE DELTA ^BETA,GAMMA )-BUTENOLIDES AVEC AMIDINES, GUANIDINES ET HYDRAZINESWOLFERS H; KRAATZ U; KORTE F et al.1973; CHEM. BER.; DTSCH.; DA. 1973; VOL. 106; NO 3; PP. 874-881; ABS. ANGL.; BIBL. 21 REF.Serial Issue

Synthesis of classical, three-carbon-bridged 5-substituted furo[2,3-d]pyrimidine and 6-substituted pyrrolo[2,3-d]pyrimidine analogues as antifolatesGANGJEE, Aleem; YIBIN ZENG; MCGUIRE, John J et al.Journal of medicinal chemistry (Print). 2004, Vol 47, Num 27, pp 6893-6901, issn 0022-2623, 9 p.Article

Rational design of 4-amino-5,6-diaryl-furo[2,3-d]pyrimidines as potent glycogen synthase kinase-3 inhibitorsMIYAZAKI, Yasushi; MAEDA, Yutaka; SATO, Hideyuki et al.Bioorganic & medicinal chemistry letters (Print). 2008, Vol 18, Num 6, pp 1967-1971, issn 0960-894X, 5 p.Article

Discovery of 4 -amino -5,6 -biaryl -furo [2,3 -d]pyrimidines as inhibitors of Lck : Development of an expedient and divergent synthetic route and preliminary SARDIMAURO, Erin F; NEWCOMB, John; XIN HUANG et al.Bioorganic & medicinal chemistry letters (Print). 2007, Vol 17, Num 8, pp 2305-2309, issn 0960-894X, 5 p.Article

Synthesis and biological evaluation of acyclic 3-[(2-hydroxyethoxy)methyl] analogues of antiviral furo- and pyrrolo[2,3-d]pyrimidine nucleosidesJANEBA, Zlatko; BALZARINI, Jan; ANDREI, Graciela et al.Journal of medicinal chemistry (Print). 2005, Vol 48, Num 14, pp 4690-4696, issn 0022-2623, 7 p.Article

Bicyclic nucleoside inhibitors of varicella-zoster virus (VZV): The effect of a terminal halogen substitution in the side-chainBRANCALE, A; MCGUIGAN, C; ANDREI, G et al.Bioorganic & medicinal chemistry letters (Print). 2000, Vol 10, Num 11, pp 1215-1217, issn 0960-894XArticle

Electrocatalytic and chemical assembling of N,N'-dialkylbarbituric acids and aldehydes: efficient cascade approach to the spiro-[furo[2,3-d]pyrimidine-6, 5'-pyrimidine]-2,2',4,4',6'-(1'H,3H,3'H)-pentone frameworkVERESHCHAGIN, Anatolii N; ELINSON, Michail N; DOROFEEVA, Evgeniya O et al.Tetrahedron (Oxford. Print). 2012, Vol 68, Num 4, issn 0040-4020, 941, 1198-1206 [10 p.]Article

Discovery of a new family of inhibitors of human cytomegalovirus (HCMV) based upon lipophilic alkyl furano pyrimidine dideoxy nucleosides: Action via a novel non-nucleosidic mechanismMCGUIGAN, Christopher; PATHIRANA, Ranjith N; SNOECK, Robert et al.Journal of medicinal chemistry (Print). 2004, Vol 47, Num 7, pp 1847-1851, issn 0022-2623, 5 p.Article

Synthesis and biological evaluation of carbon-11-labeled acyclic and furo[2,3-d]pyrimidine derivatives of bicyclic nucleoside analogues (BCNAs) for structure-brain uptake relationship study of BCNA tracersCHITNENI, Satish K; BALZARINI, Jan; CELEN, Sofie et al.Journal of labelled compounds & radiopharmaceuticals. 2008, Vol 51, Num 3, pp 159-166, issn 0362-4803, 8 p.Article

Pharmacophore modeling and in silico screening for new KDR kinase inhibitorsHUI YU; ZHANLI WANG; LIANGREN ZHANG et al.Bioorganic & medicinal chemistry letters (Print). 2007, Vol 17, Num 8, pp 2126-2133, issn 0960-894X, 8 p.Article

2'-Fluorosugar analogues of the highly potent anti-varicella-zoster virus bicyclic nucleoside analogue (BCNA) Cf 1743MCGUIGAN, Christopher; DERUDAS, Marco; QUINTILIANI, Maurizio et al.Bioorganic & medicinal chemistry letters (Print). 2009, Vol 19, Num 22, pp 6264-6267, issn 0960-894X, 4 p.Article

Synthesis and antiviral and cytostatic evaluations of the new C-5 substituted pyrimidine and furo[2,3-d]pyrimidine 4',5' -didehydro -L -ascorbic acid derivativesGAZIVODA, Tatjana; SOKCEVC, Mario; RAIC-MALIC, Silvana et al.Journal of medicinal chemistry (Print). 2007, Vol 50, Num 17, pp 4105-4112, issn 0022-2623, 8 p.Article

2,4-Diamino-5-methyl-6-substituted arylthio-furo[2,3-d]pyrimidines as novel classical and nonclassical antifolates as potential dual thymidylate synthase and dihydrofolate reductase inhibitorsGANGJEE, Aleem; JAIN, Hiteshkumar D; PHAN, Jaclyn et al.Bioorganic & medicinal chemistry. 2010, Vol 18, Num 2, pp 953-961, issn 0968-0896, 9 p.Article

Synthesis of N-[4-[1-ethyl-2-(2,4-diaminofuro[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid as an antifolateGANGJEE, Aleem; YIBIN ZENG; MCGUIRE, John J et al.Journal of medicinal chemistry (Print). 2002, Vol 45, Num 9, pp 1942-1948, issn 0022-2623Article

Synthesis and optimization of substituted furo[2,3-d]-pyrimidin-4-amines and 7H-pyrrolo[2,3-d]pyrimidin-4-amines as ACK1 inhibitorsXIANYUN JIAO; KOPECKY, David J; FARRELLY, Ellyn et al.Bioorganic & medicinal chemistry letters (Print). 2012, Vol 22, Num 19, pp 6212-6217, issn 0960-894X, 6 p.Article

Discovery of novel c-Met kinase inhibitors bearing a thieno[2,3-d]pyrimidine or furo[2,3-d]pyrimidine scaffoldAILING ZHAO; XIN GAO; YUANXIANG WANG et al.Bioorganic & medicinal chemistry. 2011, Vol 19, Num 13, pp 3906-3918, issn 0968-0896, 13 p.Article

Synthesis and preliminary evaluation of ¹⁸F-or ¹¹C-labeled bicyclic nucleoside analogues as potential probes for imaging varicella-zoster virus thymidine kinase gene expression using positron emission tomographyCHITNENI, Satish K; DEROOSE, Christophe M; BALZALINI, Jan et al.Journal of medicinal chemistry (Print). 2007, Vol 50, Num 5, pp 1041-1049, issn 0022-2623, 9 p.Article

Synthesis and evaluation of a classical 2,4-diamino-5-substituted-furo[2,3-d]pyrimidine and a 2-amino-4-oxo-6-substituted-pyrrolo [2,3 -d]pyrimidine as antifolatesGANGJEE, Aleem; JIE YANG; MCGUIRE, John J et al.Bioorganic & medicinal chemistry. 2006, Vol 14, Num 24, pp 8590-8598, issn 0968-0896, 9 p.Article

Effect of C9-methyl substitution and C8-C9 conformational restriction on antifolate and antitumor activity of classical 5-substituted 2,4-diaminofuro[2,3-d]pyrimidines¹GANGJEE, A; YIBIN ZENG; MCGUIRE, J. J et al.Journal of medicinal chemistry (Print). 2000, Vol 43, Num 16, pp 3125-3133, issn 0022-2623Article

Novel 4-amino-furo[2,3-d]pyrimidines as Tie-2 and VEGFR2 dual inhibitorsMIYAZAKI, Yasushi; MATSUNAGA, Shinichiro; NOLTE, Robert T et al.Bioorganic & medicinal chemistry letters (Print). 2005, Vol 15, Num 9, pp 2203-2207, issn 0960-894X, 5 p.Article

Synthesis of classical, four-carbon bridged 5-substituted furo[2,3-d]pyrimidine and 6-substituted pyrrolo[2,3-d]pyrimidine analogues as antifolates¹GANGJEE, Aleem; YIBIN ZENG; MCGUIRE, John J et al.Journal of medicinal chemistry (Print). 2005, Vol 48, Num 16, pp 5329-5336, issn 0022-2623, 8 p.Article